People who take proton-pump inhibitors (PPIs) like Prilosec, Prevacid, or Nexium were no more likely to die of cancer or cardiovascular, respiratory, or digestive disease over 14 years once researchers excluded those who started PPIs within 6 years of dying (since illness, not PPIs, might have raised their risk). 

An earlier 3-year clinical trial found similar results. (For more on that study, click here.)

What to do

Take PPIs, but only if you need them.