Why grapefruit doesn’t mix with some medications

In the late 1980s, researchers wanted to test whether drinking alcohol interfered with a new blood-pressure-lowering medicine called felodipine. “To make this study more scientifically valid, we tried to find a beverage that would mask the taste of the alcohol,” says David Bailey, professor emeritus of clinical pharmacology at the Schulich School of Medicine at Western University and a scientist at the Lawson Health Research Institute in Ontario, Canada.
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